2009
Samoshkin S., Arnaoutov A., Jansen L., Ouspenski I., Dye L., Karpova T., McNally J., Dasso M., Cleveland D., Strunnikov A. 2009. Human Condensin Function Is Essential for Centromeric Chromatin Assembly and Proper Sister Kinetochore Orientation. PLoS ONE 4(8): e6831.
Rafikova E., Melikov K., Ramos C., Dye L., Chernomordik L. 2009. Transmembrane protein-free membranes fuse into Xenopus nuclear envelope and promote assembly of functional pores. J. Biol Chem., 2009, Aug 20. [Epub ahead of print]
Tanaka N., Ito K., Stopfer M. 2009. Odor-Evoked Neural Oscillations in Drosophila Are Mediated by Widely Branching Interneurons. The Journal of Neuroscience. 29(26): 8595-8603.
Uveges T.E., Kozloff K.M., Ty J.M., Ledgard F., Raggio C.L., Gronowicz G., Goldstein S.A. and Marini J.C. 2009. Alendronate Treatment of Brtl Osteogenesis Imperfecta Mouse Improves Femoral Geometry and Load Response Before Fracture but Decreases Predicted Material Properties and Has Detrimental Effects on Osteoblasts and Bone Formation. J. Bone Miner. Res. 24:849-859.
Balla T. and Várnai P. 2009. Visualization of cellular phosphoinositide pools with GFP-fused protein-domains. Curr. Protoc. Cell. Biol. 24: 24-44.
Besser L., Chorin E., Sekler I., Silverman W.F., Atkin S., Russell J.T., Hershfinkel M. 2009. Synaptically released zinc triggers metabotropic signaling via a zinc-sensing receptor in the hippocampus. J. Neurosci. 29: 2890-2901.
Fisahn A., Neddens J., Yan L. and Buonanno A. 2009. Neuregulin-1 modulates hippocampal gamma oscillations: implications for schizophrenia. Cereb. Cortex. 19: 612-618.
Koshimizu H., Senatorov V., Loh Y.P. and Gozes I. 2009. Neuroprotective Protein and Carboxypeptidase E. J. Mol. Neurosci. (In Press)
Park J.J., Koshimizu H. and Loh Y.P. 2009. Biogenesis and transport of secretory granules to release site in neuroendocrine cells. J. Mol. Neurosci. 37: 151-159.
Wollert T., Wunder C., Lippincott-Schwartz J. and Hurley J.H. 2009. Membrane scission by the ESCRT-III complex. Nature. 458: 172-177.
2008
Arnaoutova I., Cawley N.X., Patel N., Kim T., Rathod T. and Loh Y.P. 2008. Aquaporin 1 is important for maintaining secretory granule biogenesis in endocrine cells. Mol. Endocrinol. 22: 1924-1934.
Baldwin G.S., Nicholas J.B., Robson R.E., Wynveen A., Goldar A., Leikin S., Seddon J.M. and A.A. Kornyshev. 2008. DNA Double Helices Recognize Mutual Sequence Homology in a Protein Free Environment. J. Phys. Chem. B, 112: 1060-1064.
Balla A., Kim Y.J., Varnai P., Szentpetery Z., Knight Z., Shokat K.M. and Balla T. 2008. Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase III alpha. Mol. Biol. Cell. 19: 711-721.
Gore A.V., Lampugnani, M.G., Dye L., Dejana, E. and Weinstein, B. 2008. Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke. Dis. Model Mech. 1: 275–281.
Han S., McBride D.J., Losert W. and Leikin S. 2008. Segregation of type I collagen homo- and heterotrimers in fibrils. J. Mol. Biol. 383: 122-132.
Ito I., Ong R.C., Raman B. and Stopfer M. 2008. Sparse odor representation and olfactory learning. Nat. Neurosci. 11: 1177-1184.
Jung S.C., Kim J. and Hoffman D.A. 2008. Rapid, bidirectional remodeling of synaptic NMDA receptor subunit composition by A-type K+ channel activity in hippocampal CA1 pyramidal neurons. Neuron. 60: 657-671.
Kim S.J., Zhang Z., Sarkar C., Tsai, P.C., Lee Y.C., Dye L. and Mukherjee A. 2008. Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice. J. Clin. Investigation. 118: 3075-3086.
Kwon O.B., Paredes D., Gonzalez C.M., Neddens J., Hernandez L., Vullhorst D. and Buonanno A. 2008. Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors. Proc. Natl. Acad. Sci. 105: 15587-15592.
Park J.J., Cawley N.X. and Loh Y.P. 2008. Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. Mol. Endocrinol. 22: 989-1005.
Park J.J., Cawley N.X. and Loh Y.P. 2008. A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons. Mol. Cell Neurosci. 39: 63-73.
Porrás A., Kozar S., Russanova V., Salpea P., Hirai T., Sammons N., Mittal P., Kim J.Y., Ozato K., Romero R. and Howard B.H. 2008. Developmental and epigenetic regulation of the human TLR3 gene. Mol. Immunol. 46: 27-36.
Woronowicz A., Koshimizu H., Chang S.Y., Cawley N.X., Hill J.M., Rodriguiz R.M., Abebe D., Dorfman C., Senatorov V., Zhou A., Xiong Z.G., Wetsel W.C. and Loh Y.P. 2008. Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits. Hippocampus. 18: 1051-1063.
Zemkova H.W., Bjelobaba I., Tomic M., Zemkova H. and S.S. Stojilkovic.2008. Molecular, pharmacological and functional properties of GABAA receptors in anterior pituitary cells. J. Physiol 586: 3097–3111.
2007
Forlino A., Kuznetsova N.V., Marini J.C. and S. Leikin. 2007. Selective retention and degradation of molecules with a single mutant alpha1(I) chain in the Brtl IV mouse model of OI. Matrix Biol. 26: 604-614.
Hatae N., Aksentijevich N., Zemkova H.W., Kretschmannova K., Tomic M. and S.S. Stojilkovic. 2007. Cloning and functional identification of novel endothelin receptor type A isoforms in pituitary. Mol. Endocrinol. 21: 1192-1204.
Karavanova I., Vasudevan K., Cheng J. and A. Buonanno. 2007. Novel regional and developmental NMDA receptor expression patterns uncovered in NR2C subunit-beta-galactosidase knock-in mice. Mol. Cell. Neurosci. 34: 468-480.
Kim J., Jung S.C., Clemens A., Petralia R. and D. Hoffman. 2007. Regulation of dendritic excitability by activity-dependent trafficking of the A-type K+ channel subunit Kv4.2 in hippocampal neurons. Neuron. 54: 933-947
Lou H., Smith A.M., Coates L.C., Cawley N.X. and Y.P. Loh. 2007. The transmembrane domain of the prohormone convertase PC3: A key motif for targeting to the regulated secretory pathway. Molecular and Cellular Endocrinology. 267: 17-25.
Luo T., Xu Y., Hoffman T.L., Zhang T., Schilling T. and T.D. Sargent. 2007. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Development. 134: 1279-1289.
Ong H.L., Liu X., Tsaneva-Atanasova K., Singh B.B., Bandyopadhyay B.C., Swaim W.D., Russell J.T., Hegde R.S., Sherman A. and I.S. Ambudkar. 2007. Relocalization of STIM1 for activation of store-operated Ca(2+) entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca(2+) store. J. Biol. Chem. 282: 12176-12185.
Ong H.L., Liu X., Sharma A., Hegde R.S. and I.S. Ambudkar. 2007. Intracellular Ca(2+) release via the ER translocon activates store-operated calcium entry. Pflugers Arch. 453: 797-808.
Pelkey K.A, Yuan X., Lavezzari G., Roche K.W. and McBain C.J. 2007. mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082. Neuropharmacology. 52: 108-117.
Stefanovic B., Hutchinson E., Yakovleva V., Schram V., Russell J.T., Belluscio L., Koretsky A.P. and A.C. Silva. 2007. Functional reactivity of cerebral capillaries. J. Cereb. Blood Flow Metab. 1-12.
Toews J., Schram V., Weerth S.H., Mignery G.A. and Russell J.T. 2007. Signaling proteins in the axoglial apparatus of sciatic nerve nodes of Ranvier. Glia 55: 202-213.
van de Leemput J., Chandran J., Knight M.A., Holtzclaw L.A., Scholz S., Cookson M.R., Houlden H., Gwinn-Hardy K., Fung H.C., Lin X., Hernandez D., Simon-Sanchez J., Wood N.W., Giunti P., Rafferty I., Hardy J., Storey E., Gardner R.J., Forrest S.M., Fisher E.M., Russell J.T., Cai H. and Singleton A.B. 2007. Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. PLoS Genet. 3: e108.
Várnai P., Tóth B., Tóth D.J., Hunyady L. and T. Balla. 2007. Visualization and manipulation of plasma membrane-endoplasmic reticulum contact sites indicates the presence of additional molecular components within the STIM1-Orai1 Complex. J. Biol. Chem. 282: 29678-29690.
Vermeire K., Lisco A., Grivel J.C., Scarbrough E., Dey K., Duffy N., Margolis L., Bell T.W. and D. Schols. Design and cellular kinetics of dansyl-labeled CADA derivatives with anti-HIV and CD4 receptor down-modulating activity. Biochem Pharmacol. 74: 566-578.
Yagi R., Kohn M.J., Karavanova I., Kaneko K.J., Vullhorst D., DePamphilis M.L. and A. Buonanno. 2007. Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development. Development. 134: 3827-3836.
Zemkova H., Yan Z., Liang Z., Jelinkova I., Tomic M. and S.S. Stojilkovic. 2007. Role of aromatic and charged ectodomain residues in the P2X(4) receptor functions. J. Neurochem. 102: 1139-1150.
2006
Balazs T., Ball A., Ma H., Knight Z.A., Shokat K.M., Balla T. 2006. Phosphatidylinositol 4-kinase regulates the transport of ceramide between the endoplasmic reticulum and golgi. J. Biol. Chem. (In Press).
Gondre-Lewis, M., Petrache, H., Wassif, C., Harries, D., Parsegian, A., Porter, F. and Loh Y.P. 2006 Abnormal sterols cause secretory granule malformation in cholesterol deficiency diseases and decreased membrane curvature. J Cell Science. 119: 1876-1885.
Kamei M, Saunders B, Bayless K, Dye L, Davis G, Weinstein B, 2006. Endothelial tubes assemble from intracellular vacuoles in vivo. Nature 442: 6554-6559.
Kim, T., Gondre-Lewis, M., Arnaoutova, I. and Loh Y.P. 2006. Dense-core Secretory Granule Biogenesis. Physiology 21: 124-133.
Kim T, Loh YP. 2006. Protease Nexin-1 regulates granule protein stability and secretory granule biogenesis at the golgi. Mol Biol Cell. 17: 789-798.
Lou, H., Smith, A., Coates, L., Loh Y.P. and Birch, N. 2006. The transmembrane domain of the prohormone convertase PC3: A key motif for targeting to the regulated secretory pathway. Mol & Cellular Endocrinology (under revision).
Mavrakis, M., Lippincott-Schwartz, J., Stratakis, C.A., and Bossis, I. 2006. Depletion of type IA regulatory subunit (RIa) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency. Human Molecular Genetics 15: 2962-2971.
Pelkey, K.A., Yuan X.-Q., Lavezzari, G., Roche, K.W., & McBain, C.J. 2006. mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082. Neuropharmacology 52, 108-117.
Pham, V. N., Lawson, N. D., Mugford, J., Dye, L., Castranova, D. A., Lo, B. D., and Weinstein, B. M. 2006. Combinatorial function of ETS transcription factors in the developing vasculature. Developmental Biology (In Press).
Plosky B.S., Vidal1 A.E., Henestrosa A.R.F., McLenigan M.P., McDonald J.P., Mead S., Woodgate R. 2006. Controlling the subcellular localization of DNA polymerases i and g via interactions with ubiquitin. EMBO J. 25: 2847–2855.
Varnai P., Thyagarajan B., Rohacs T., Balla T. 2006. Rapidly inducible changes in phosphatidylinositol 4,5-biphosphate levels influence multiple regulatory functions of the lipid in intact living cells. J. Cell Biol. 175: 377-382.
Yan Z, Liang Z, Obsil T, Stojilkovic SS. 2006. Participation of the lys313-ile333 sequence of the P2X4 receptor in agonist binding and transduction of signals to the channel gate. J Biol Chem 281: 32649-32659.
Yaniv K, Isogai S, Castranova D, Dye L, Hitomi J, Weinstein B, 2006. Live imaging of lymphatic development in the zebrafish. Nature Medicine (12, 711-716.).
Yanik T, Dominguez G, Kuhar MJ, Del Giudice EM, Loh YP. 2006. The Leu34Phe ProCART mutation leads to cocaine- and amphetamine-regulated transcript (CART) deficiency: a possible cause for obesity in humans. Endocrinology. 147: 39-43.
2005
Kim T, Zhang CF, Sun Z, Wu H, Loh YP. 2005. Chromogranin A deficiency in transgenic mice leads to aberrant chromaffin granule biogenesis. J Neurosci. 25: 6958-6961.
Kino T, Tiulpakov A, Ichijo T, Chheng L, Kozasa T, Chrousos GP. 2005. G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus. J Cell Biol. 169: 885-896.
Kino T, Kozasa T, Chrousos GP. 2005. Statin-induced blockade of prenylation alters nucleocytoplasmic shuttling of GTP-binding proteins gamma2 and beta2 and enhances their suppressive effect on glucocorticoid receptor transcriptional activity. Eur J Clin Invest. 35: 508-513.
Kwon OB, Longart M, Vullhorst D, Hoffman DA, Buonanno A. 2005. Neuregulin-1 reverses long-term potentiation at CA1 hippocampal synapses. J Neurosci. 25: 9378-9383.
Mavrakis, M., Lippincott-Schwartz, J., Stratakis, C.A., and Bossis, I. 2006. Depletion of type IA regulatory subunit (RIa) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency. Human Molecular Genetics 15: 2962-2971.
Olivares-Reyes JA, Shah BH, Hernandez-Aranda J, Garcia-Caballero A, Farshori MP, Garcia-Sainz JA, Catt KJ. 2005. Agonist-induced interactions between angiotensin AT1 and epidermal growth factor receptors. Mol Pharmacol. 68: 356-364.
Sidhu G, Li W, Laryngakis N, Bishai E, Balla T, Southwick F. 2005. Phosphoinositide 3-kinase is required for intracellular Listeria monocytogenes actin-based motility and filopod formation. J Biol Chem. 280: 11379-11386.
Varnai P, Balla A, Hunyady L, Balla T. 2005. Targeted expression of the inositol 1,4,5-triphosphate receptor (IP3R) ligand-binding domain releases Ca2+ via endogenous IP3R channels. Proc Natl Acad Sci U S A. 102: 7859-7864.
Varnai P, Bondeva T, Tamas P, Toth B, Buday L, Hunyady L, Balla T. 2005. Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners. J Cell Sci. 118: 4879-4888.
Yan Z, Liang Z, Tomic M, Obsil T, Stojilkovic SS. 2005. Molecular determinants of the agonist binding domain of a P2X receptor channel. Mol Pharmacol. 67: 1078-1088.
Zhu X, Wu K, Rife L, Cawley NX, Brown B, Adams T, Teofilo K, Lillo C, Williams DS, Loh YP, Craft CM. 2005. Carboxypeptidase E is required for normal synaptic transmission from photoreceptors to the inner retina. J Neurochem. 95:1351-1362.
2004
Kino T, Liou SH, Charmandari E, Chrousos GP. 2004. Glucocorticoid receptor mutants demonstrate increased motility inside the nucleus of living cells: time of fluorescence recovery after photobleaching (FRAP) is an integrated measure of receptor function. Mol Med. 10: 80-88.
Tang J, Stern-Nezer S, Liu PC, Matyakhina L, Riordan M, Luban NL, Steinbach PJ, Kaler SG. 2004. Mutation in the leucine-rich repeat C-flanking region of platelet glycoprotein Ib beta impairs assembly of von Willebrand factor receptor. Thromb Haemost. 92: 75-88.
